MiRNAs with prognostic significance in multiple myeloma
نویسندگان
چکیده
منابع مشابه
Prognostic Factors in Patients with Multiple Myeloma
That is why the morphology of myeloma cells is one of the most important prognostic factors of the disease [4]. There are also other prognostic factors associated with both malignant cell characteristics and the status of the host's immunocompetent system [7]. Taking into account the data on the decrease in colony-forming units granulocyte/macrophage (CFU-OM) in MM [2, 11], an~ the antitumor ef...
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All patients with multiple myeloma seen over a 9-year period at Tygerberg Hospital were studied retrospectively. Presentation data of 144 patients, as well as individual laboratory results were included in the survival analysis. Cox's proportional hazard model (a non-parametric multivariate regression method) was used to predict survival and divide patients into prognostic groups. The relations...
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BACKGROUND Magnetic resonance imaging (MRI) has been a useful technique for the assessment of patients with multiple myeloma (MM). We evaluated the prognostic significance of different MRI patterns in symptomatic patients with MM. PATIENTS AND METHODS A total of 142 symptomatic MM patients underwent MRI before treatment. MRI patterns of involvement were correlated with known prognostic variab...
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BACKGROUND Bortezomib administration leads to a transient decrease in CD4(+) T cells, increasing the susceptibility to opportunistic infections. The activation and proliferation of CD4(+) T cells are particularly important in the host's defense against tuberculosis infection. The aim of this study was to determine the incidence and clinical significance of tuberculosis infection in patients wit...
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The therapy for multiple myeloma has made major strides over the last 15 years, by and large due to the advances in molecular biology and the focus on patient-oriented translational investigations. Although the survival outcomes have improved significantly, clinical features such as older age, renal insufficiency at diagnosis, primary plasma cell leukemia and extramedullary disease remain major...
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ژورنال
عنوان ژورنال: Medicine
سال: 2019
ISSN: 0025-7974,1536-5964
DOI: 10.1097/md.0000000000016711